In all honesty it'll be difficult to even make an informed decision until the potential of each engine has been reached and the weaknesses discovered.
The I4 is very similar to the 4B11T in the EVO X, so a lot of the knowledge from R&D on that engine will transfer over, or at least apply well enough that tuning companies won't have to start from scratch.
The V6 can probably hit 450whp supercharged (and there will be companies supercharging the V6) but nobody will know how much power the V6 will hold until people exceed the amount and start blowing them up.
The popular opinion is that the I4 will have more potential to make big power, and that the point where the I4 makes more sense than the V6 would be somewhere around the 450whp mark. This is however speculation, if the V6 holds to 500whp or 600whp there won't be much of a reason to mod the I4.
There is a good chance that you will be able to make the I4 faster than the V6 for less money than buying a V6 Genesis Coupe also which would be another reason some people would opt for the I4. Since it's already FI it's easier to work on upping the power than switching a NA car to FI.
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